Hongrui Guo

Identity

 ·  Associate Professor   

Education

 · 03/2013-12/2018, PhD in Basic Veterinary Medicine, Sichuan Agricultural University

 · 09/2009-06/2013, B.S. in Veterinary Medicine, Sichuan Agricultural University

Training and Professional Experience

·  11/2022-now, Associate Professor, Sichuan Agricultural University College of Veterinary Medicine

·  12/2018-11/2022, Lecturer, Sichuan Agricultural University College of Veterinary Medicine

Research Interests

·  Focus on Animal mineral element metabolic diseases and poisoning diseases.

Selected Publications 

·  Hongrui Guo#; Yujuan Ouyang#; Jiaqi Wang#; Hengmin Cui*; Huidan Deng*; Xinyue Zhong; Zhijie Jian; Huan Liu; Jing Fang; Zhicai Zuo; Xun Wang; Ling Zhao; Yi Geng; Ping Ouyang; Huaqiao Tang; Cu-induced spermatogenesis disease is related to oxidative stress-mediated germ cell apoptosis and DNA damage, Journal of Hazardous Materials, 2021, 416: 125903.

·  Hongrui Guo#; Yujuan Ouyang#; Heng Yin#; Hengmin Cui*; Huidan Deng*; Huan Liu; Zhijie Jian; Jing Fang; Zhicai Zuo; Xun Wang; Ling Zhao; Yanqiu Zhu; Yi Geng; Ping Ouyang; Induction of autophagy via the ROS-dependent AMPK-mTOR pathway protects copper-induced spermatogenesis disorder, Redox Biology, 2022, 49: 102227.

·  Hongrui Guo#; Hai Guo#; Yue Xie; Yinyin Chen; Changfang Lu; Zhouping Yang; Yanqiu Zhu; Yujuan Ouyang; Yu Zhang; Xianxiang Wang*; Mo3Se4 nanoparticle with ROS scavenging and multi-enzyme activity for the treatment of DSS-induced colitis in mice, Redox Biology, 2022, 56: 102441.

·  Christine Quach#; Ying Song#; Hongrui Guo#; Shun Li; Hadi Maazi; Marshall Fung; Nathaniel Sands; Douglas O’Connell; Sara Restrepo-Vassalli; Billy Chai; Dali Nemecio; Vasu Punj; Omid Akbari; Gregory E Idos; Shannon M. Mumenthlar; Nancy Wu; Sue Ellen Martin; Ashley Hagiya; James Hicks; Hengmin Cui; Chengyu Liang*; A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nature Communications, 2019, 10(1):5681.

·  Hongrui Guo#; Zhicai Zuo#; Fengyuan Wang#; Caixia Gao#; Kejie Chen*; Jing Fang*; Hengmin Cui; Ping Ouyang; Yi Geng; Zhengli Chen; Chao Huang; Yanqiu Zhu; Huidan Deng, Attenuated cardiac oxidative stress, inflammation and apoptosis in obese mice with nonfatal infection of Escherichia coli, Ecotoxicology and Environmental Safety, 2021, 225, 112760.

·  Qin Luo; Yuzhen Song; Jingjing Kang; Yuchen Wu; Fengsun Wu; Yueqin Li; Qing Dong; Jun Wang; Chao Song; Hongrui Guo*; mtROS-mediated Akt/AMPK/mTOR pathway was involved in Copper-induced autophagy and it attenuates Copper-induced apoptosis in RAW264.7 mouse monocytes, Redox Biology , 2021, 41:101912.

·  Hongrui Guo^#; Zhijie Jian^#; Huan Liu^#; Hengmin Cui^#*; Huidan Deng^*; Jing Fang; Zhicai Zuo; Xun Wang; Ling Zhao; Yi Geng; Ping Ouyang; Huaqiao Tang ; TGF-beta 1-induced EMT activation via both Smad-dependent and MAPK signaling pathways in Cu-induced pulmonary fibrosis, Toxicology and Applied Pharmacology, 2021, 418:115500

·  Hongrui Guo^#; Yuqin Wang^#; Hengmin Cui^#; Yujuan Ouyang; Tingyou Yang; Caiyun Liu; Xiaoyu Liu; Yanqiu Zhu; Huidan Deng^*; Copper induces spleen damage through modulation of oxidative stress, apoptosis, DNA damage, and inflammation, Biological Trace Element Research, 2022, 200(2): 669-67.

·  Hongrui Guo^#; Huidan Deng^#; Huan Liu^#; Zhijie Jian; Hengmin Cui^*; Jing Fang; Zhicai Zuo; Junliang Deng; Yinglun Li; Xun Wang; Ling Zhao, Nickel carcinogenesis mechanism: cell cycle dysregulation, Environmental Science and Pollution Research, 2020, 28(5): 4893-4901

·  Huan Liu^#; Huidan Deng^#; Zhijie Jian^#; Hengmin Cui^*; Hongrui Guo^*; Jing Fang; Zhicai Zuo; Junliang Deng; Yinglun Li; Xun Wang; Ling Zhao; Yanqiu Zhu; Copper exposure induces hepatic G0/G1 cell-cycle arrest through suppressing the Ras/PI3K/Akt signaling pathway in mice, Ecotoxicology and Environmental Safety 2021, 222: 112518.