Xiaobo Huang

Identity

·  Professor

·  Director of Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University

·  Vice Director, Research center for swine diseases, College of Veterinary Medicine, Sichuan Agricultural University

Education

·  09/2003-06/2006, PhD in in Veterinary Microbiology, Sichuan Agricultural University

·  09/2000-06/2003, M.S. in Veterinary Microbiology, Sichuan Agricultural University

·  09/1996-06/2000, B.S. in Veterinary Medicine, Sichuan Agricultural University

Training and Professional Experience

·  03/2016-03/2017 Visiting Scholar, Food Animal Health Research Center, Ohio state University

·  09/2014 -12/2014，English training, Sichuan University

Research Interests

·  Focus on the epidemiology, pathogenesis, novel vaccine and diagnostic kits of swine coronavirus (PEDV, PDCoV, TGEV, etc) and other enteric virus.

·  Clinical Precise prevention and control technology of swine disease.

Awards and Honors

·  The 2nd Prize for Science and Technology Progress Award of Sichuan Province, Research on zoonotic pathogen and risk in Sichuan earthquake stricken areas. Sichuan Provincial People's Government,2013.

·  "Excellent Paper Award" (twice) and "Excellent Paper Nomination Award" of Chinese Society of Animal Husbandry and Veterinary Medicine .

Selected Publications

·  Yujia Zhao,Rui Chen,Dai Xiao, Luwen Zhang, Daili Song, Yiping Wen , Rui Wu, Qin Zhao,Senyan Du, Xintian Wen, Sanjie Cao ,Xiaobo Huang*. A Comparative Transcriptomic Analysis Reveals That HSP90AB1 Is Involved in the Immune and Inflammatory Responses to Porcine Deltacoronavirus Infection.International Journal of Molecular Sciences.2022,23,3280.

·  Qu H, Wen Y, Hu J, Xiao D, Li S, Zhang L, Liao Y, Chen R, Zhao Y, Wen Y, Wu R, Zhao Q, Du S, Yan Q, Wen X, Cao S, Huang X*. Study of the inhibitory effect of STAT1 on PDCoV infection[J]. Veterinary Microbiology, 2022 Mar; 266: 109333.

·  Zhao Y, Xiao D, Zhang L, Song D, Chen R, Li S, Liao Y, Wen Y, Liu W, Yu E, Wen Y, Wu R, Zhao Q, Du S, Wen X, Cao S, Huang X *. HSP90 inhibitors 17-AAG and VER-82576 inhibit porcine deltacoronavirus replication in vitro[J]. Veterinary Microbiology, 2022 Feb; 265: 109316.

·  Li S, Xiao D, Zhao Y, Zhang L, Chen R, Liu W, Wen Y, Liao Y, Wen Y, Wu R, Han X, Zhao Q, Du S, Yan Q, Wen X, Cao S, Huang X*. Porcine Deltacoronavirus (PDCoV) Entry into PK-15 Cells by Caveolae Mediated Endocytosis[J]. Viruses. 2022; 14(3): 496.

·  Chen R，Fu J, Hu J, Li C, Zhao Y, Qu H; Wen X, Cao S,Wen Y,Wu R; Zhao Q, Yan Q,Huang, Y, Ma X, Han X, Huang X*; Identifcation of the immunodominant neutralizing regions in the spike glycoprotein of porcine deltacoronavirus, Virus Research, 2020, 276: 197834-197843.https://doi.org/10.1016/j.virusres.2019.197834

·  Zhao Yujia,Qu Huan, Hu Jingfei,Fu Jiayu,Chen Rui, Li Cheng,Cao Sanjie, Wen Yiping,Wu Rui, ZhaoQin,Yan Qigui, Wen Xintian, Huang Xiaobo*. Characterization and Pathogenicity of the Porcine Deltacoronavirus Isolated in Southwest China , Viruses, 2019, 11(11): 1074-1096. doi:10.3390/v11111074

·  Jiayu Fu,Rui Chen,Jingfei Hu,Huan Qu,Yujia Zhao,Sanjie Cao,Xintian Wen,Yiping Wen,Rui Wu,Qin Zhao,Xiaoping Ma,Xiaobo Huang*.Identification of a Novel Linear B-Cell Epitope on the Nucleocapsid Protein of Porcine Deltacoronavirus. International Journal of Molecular Sciences. 2020, 21, 648; doi:10.3390/ijms21020648.

·  Yudi Zhang,Xiaohui Zhang,Xiaodan Zhang,Xiaobo Huang*,Sanjie Cao,Xintian Wen,Yipping Wen,Ruiwu,Wumei Liu.Construction of a bivalent DNA vaccine co-expressing S-genes of transmissible gastroenteritis virus and porcine epidemic diarrhea virus delivered by attenuated Salmonella typhimurium.Virus Genes,2016, 52(3):354-364.

·  Ying Q, Liu J, Xiaobo Huang*,Yaqing Li ,Yudi Zhang,Jie Chen,Xintian Wen,Sanjie Cao,Yiping Wen,Rui Wu. Immunogenicity of transmissible gastroenteritis virus (TGEV) M gene delivered by attenuated Salmonella typhimurium in mice[J]. Virus Genes, 2016:1-10.

·  Dan Zhang, Xiaobo Huang*, Xiaohui Zhanga, Sanjie Cao, Xintian Wen, Yiping Wen, Rui Wu, Entao Liang Construction of an oral vaccine for transmissible gastroenteritis virus based on the TGEV N gene expressed in an attenuated Salmonella typhimurium vector[J].Journal of Virological Methods, 2016, 227.

·  Heng Yang, Sanjie Cao, Xiaobo Huang,et al. Intragastric administration of attenuated Salmonella typhimurium harbouring transmissible gastroenteritis virus (TGEV) DNA vaccine induced specific antibody production[J]. vaccine,2009,7(27)：5035–5040.