Hui Wang

Identity

· Associate Professor

Education

· 09/2011-06/2015, PhD in Preventive Veterinary Medicine, China Agricultural University

· 09/2009-06/2011, M.S. in Preventive Veterinary Medicine, China Agricultural University

· 09/2005-06/2009, B.S. in Animal and Plant Quarantine, Sichuan Agricultural University

Training and Professional Experience

· 07/2023-Present, Associate Professor, College of Veterinary Medicine, Sichuan Agricultural University

· 04/2018-03/2023, Postdoc, School of Life Sciences, Peking University

· 07/2015-03/2018, Lecturer, Department of Pathogenic Biology, Chengdu Medical College

Research Interests

· Field of interest is to decode the cryptic mechanisms of reprograming or remodeling the host transcription and chromatin structures through the nuclear factors of Toxoplasma gondii (also including Echinococus granulosus, Trypanosoma Cruzi and Trichinella spiralis) during infection. Current and future works focus on the secretion factors of these parasites and its functions within host nucleus, as well as to evaluate its potential possibility of vaccination and therapeutic target.

Awards and Honors

· Poster Award in 11^th International Coccidiosis Conference, Dresden, Germany

Selected Publications

· Wang H^#, Li B^#, Zuo L, Wang B, Yan Y, Tian K, Zhou R, Wang C, Chen X, Jiang Y, Zheng H, Qin F, Zhang B, Yu Y, Liu CP, Xu Y, Gao J, Qi Z, Deng W, Ji X*. The transcriptional coactivator RUVBL2 regulates Pol II clustering with diverse transcription factors. Nature Communications, 2022, 13(1): 5703.

· Wang H^#*, Zhou R^#, Ji X*. Droplet formation assay for investigating phase separation mechanisms of RNA Pol II transcription and CTCF functioning. STAR Protocols, 2023, 4(2): 102202.

· Wang H, Li M, Liu J, Xu J, Han Q, Liu Q*. Toxoplasma gondii Infection Induces High Mobility Group Box 1 Released from Mouse Macrophages. Frontiers in Microbiology, 2017, 8: 658.

· Wang H, Lei T, Liu J, Li M, Nan H, Liu Q*. A nuclear factor of high mobility group box protein in Toxoplasma gondii. PLoS One, 2014, 9(11): e111993.

· Qin F^#*, Li B^#, Wang H, Ma S, Li J, Liu S, Kong L, Zheng H, Zhu R, Han Y, Yang M, Li K, Ji X*, Chen P*. Single-site-resolved multi-omics links chromatin mark-defined proteome and genome in living cells. Cell, 2023, 186 (5): 1066-1085.

· Li Y^#, Huang J^#, Zhu J, Bao L, Wang H, Jiang Y, Tian K, Wang R, Zheng H, Duan W, Lai W, Yi X, Zhu Y, Guo T, Ji X*. Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity. Molecular Cell, 2022, 82(20): 3943-3959.e11.

· Li M, Wang H, Liu J, Hao P, Ma L, Liu Q*. The Apoptotic Role of Metacaspase in Toxoplasma gondii. Frontiers in Microbiology, 2016, 6: 1560.

· Qian W, Wang H, Shan D, Li B, Liu J, Liu Q*. Activity of several kinds of drugs against Neospora caninum. Parasitology International, 2015, 64(6): 597-602.

· Qian W, Wang H, Su C, Shan D, Cui X, Yang N, Lv C, Liu Q*. Isolation and characterization of Toxoplasma gondii strains from stray cats revealed a single genotype in Beijing, China. Veterinary Parasitology, 2012, 187(3-4): 408-413.